Aspergillosis
Aspergillosis is a fungal infection caused by Aspergillus species (primarily A. fumigatus) that primarily affects the respiratory system. In birds, it is one of the most common and serious infectious diseases, affecting the air sacs and lungs. In dogs, it typically presents as nasal aspergillosis (sinonasal infection) or disseminated aspergillosis.
Symptoms & Signs
- Birds: difficulty breathing, tail bobbing, voice change, weight loss, lethargy
- Dogs (nasal): chronic nasal discharge, sneezing, facial pain, depigmentation of nares
- Dogs (disseminated): lameness, back pain, fever, weight loss, organ failure
Causes & Risk Factors
Aspergillus spores are ubiquitous in the environment. Immunocompromised individuals are most susceptible. In birds: stress, poor ventilation, overcrowding, concurrent illness. In dogs: nasal form often occurs in dolichocephalic breeds; disseminated form associated with immunosuppression.
Diagnosis
Birds: radiographs/CT showing air sac thickening, endoscopy with biopsy, Aspergillus antigen testing. Dogs (nasal): rhinoscopy showing fungal plaques, CT imaging, fungal culture, serology. Dogs (disseminated): urine Aspergillus antigen, tissue biopsy.
Treatment
Birds: antifungal therapy (voriconazole, itraconazole, amphotericin B nebulization), supportive care, environmental correction. Dogs (nasal): topical clotrimazole infusion via trephination, systemic antifungals. Dogs (disseminated): long-term systemic antifungals (poor prognosis).
Prevention
Birds: proper ventilation, clean environment, minimize stress, quarantine new birds, avoid moldy bedding/food. Dogs: no specific prevention for nasal form. Maintain immune health.
Prognosis
Birds: guarded; early detection improves outcomes but mortality remains significant. Dogs (nasal): good with topical treatment (80-90% cure rate). Dogs (disseminated): poor, often fatal despite treatment.
Affected Breeds (10)
| Breed | Species | Size |
|---|---|---|
| African Grey Parrot | Bird | Medium |
| Alexandrine Parakeet | Bird | Medium |
| Blue-fronted Amazon | Bird | Medium |
| Blue-headed Pionus | Bird | Medium |
| Green-cheeked Conure | Bird | Small |
| Hawk-headed Parrot (Red-fan) | Bird | Medium |
| Indian Ringneck Parakeet | Bird | Medium |
| Scarlet Macaw | Bird | Large |
| Senegal Parrot | Bird | Medium |
| Yellow-naped Amazon | Bird | Medium |