Dilated Cardiomyopathy
Dilated Cardiomyopathy (DCM) is a primary myocardial disease characterized by dilation of the heart chambers and impaired systolic (contractile) function. The heart muscle becomes thin and weak, unable to pump blood effectively. It is the second most common heart disease in dogs, predominantly affecting large and giant breeds.
Symptoms & Signs
- Exercise intolerance
- Coughing (especially at night)
- Rapid or labored breathing
- Abdominal distension (ascites)
- Weakness or collapse
- Loss of appetite and weight loss
- Irregular heart rhythm
- Sudden death (especially in Dobermans)
Causes & Risk Factors
Most cases are idiopathic with strong genetic predisposition. Known genetic mutations exist in some breeds (Doberman, Boxer). Nutritional deficiency (taurine, L-carnitine) causes reversible DCM in some breeds. Recent concerns about grain-free diets and DCM are under investigation.
Diagnosis
Echocardiography reveals chamber dilation and reduced fractional shortening (<25%). Holter monitoring detects arrhythmias. Chest radiographs show cardiomegaly and pulmonary edema. Cardiac biomarkers (NT-proBNP, troponin) aid early detection.
Treatment
Pimobendan (positive inotrope/vasodilator) is the cornerstone of therapy. ACE inhibitors, diuretics (furosemide, spironolactone), and antiarrhythmics as needed. Taurine/L-carnitine supplementation if deficient. Sodium-restricted diet.
Prevention
Genetic screening in predisposed breeds. Annual cardiac screening (echocardiography, Holter) for at-risk breeds. Ensuring adequate taurine in diet. Early detection through screening programs (Doberman occult DCM screening).
Prognosis
Guarded to poor once clinical signs develop. Median survival with treatment is 6-24 months depending on breed and stage at diagnosis. Dobermans have shorter survival times. Taurine-deficient DCM may be partially reversible.
Affected Breeds (10)
| Breed | Species | Size |
|---|---|---|
| Balinese | Cat | Medium |
| Borzoi | Dog | Giant |
| Boxer | Dog | Large |
| Dalmatian | Dog | Medium |
| Doberman Pinscher | Dog | Large |
| English Mastiff | Dog | Giant |
| Great Dane | Dog | Giant |
| Leonberger | Dog | Giant |
| Saint Bernard | Dog | Giant |
| Standard Schnauzer | Dog | Medium |